

Cosmelan
Cosmelan by Mesoesetetic® is the world’s leading treatment program that brightens and evens skin tone while preventing their reappearance. With an exclusive combination of active ingredients, Cosmelan acts as an enzyme in the melanocyte to correct and regulate the production of melanin.
This inhibits the activation of tyrosinase and reduces the amount of melanin synthesised for skin that is visibly clearer, brighter and more radiant. The complete programme includes an intense in-clinic treatment which is then supported with a home skincare regime.
How does it work?
The Cosmelan® formula contains an exclusive combination of active ingredients with proven efficacy, which act on all stages of the hyperpigmentation process to completely eliminate existing hyperpigmentations, preventing both their reappearance and the appearance of new dark spots.
Regulating Action
Cosmelan® works at two levels: At the first level by inhibiting the activation of tyrosinase inside the melanosome, reducing the oxidative stress, and thereby reducing melanin synthesis; at a second level, by containing copper chelators (Cu2+) tyrosinase function is reduced. Cosmelan® acts by blocking the transfer of the melanosome to the keratinocytes, thereby preventing movement of the pigment to the superficial layers of the skin.
Corrective Action
It acts by reducing the amount of melanin synthesized, reducing the intensity of the dark spot. It also acts on the stratum corneum, stimulating the renewal of the epidermis and intensively eliminating the accumulation of melanin.
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